While V-twin motorcycles are typically known for their torque and power delivery rather than outright top speed, the Panigale V4 R is a high-performance sportbike that can reach impressive speeds.
The Ducati Panigale V4 R is equipped with a 998cc V4 engine that produces around 221 horsepower (234 horsepower with the racing kit) and features advanced aerodynamics and racing technology. While specific top speeds may vary based on factors such as rider weight, aerodynamic modifications, and riding conditions, the Panigale V4 R is capable of reaching speeds over 185 mph (298 km/h) in stock form.
It's worth noting that the motorcycle industry is continuously evolving, and new models are introduced regularly. Therefore, there may be other V-twin motorcycles or even newer versions of existing models that claim to be the fastest V-twin motorcycles by the time of your inquiry.